01 // the challenge

The evidence base is too large to read. Too important to skip.

Evidence explosion

8,000+ immunotherapy papers, doubling every 18 months. No human can read fast enough to stay current.

Biomarker proliferation

PD-L1, TMB, MSI-H, dMMR โ€” which claims survive cross-reference? Which are overfitted to small cohorts?

Trial design pressure

Phase 3 trials cost $50M+. You need evidence synthesis before commitment, not after enrollment.

02 // the axion approach

Evidence synthesis that survives adversarial review.

8,269 papers indexed

8,269-paper immunotherapy corpus

Checkpoint inhibitors, CAR-T, combination therapies. PubMed-sourced and indexed by mechanism.

2+ independent model families

Adversarial claim testing

Independent model families attack your synthesis on mechanism, evidence, and feasibility before a reviewer does.

every doi checked

Citation verification

Every DOI is checked against live databases before delivery. Fabricated or mismatched references are flagged.

03 // results

What the pipeline produces.

8,269 papers analyzed
2+ independent model families
what a review covers

Combination therapy evidence review: PD-1/CTLA-4 combination evidence across a large paper set is checked for contradictions in published response rates and for safety signals that post-hoc analyses under-report, before Phase 2 design.

04 // start

Research audit for immunotherapy work.

Send one hypothesis, evidence question, or draft section. We run it through the adversarial pipeline and show you what survives.

One hypothesis or evidence question. We confirm review scope before work starts.

explore