what is inside
01
10 Common Objections
- Problem undefined
- Incremental innovation
- Underpowered
- Unrealistic timeline
- No preliminary data
- PI expertise gap
- No disease track record
- Cohort access unclear
- Effort mismatch
- Equipment unjustified
02
Self-Review Rubric
- Score each criterion 1-9
- Compare vs likely reviewer
- Gap >2 = underestimating
- All 5 NIH criteria
03
Red Flag Detector
- Aim dependency
- Sex as variable (NOT-OD-15-102)
- Stats plan per aim
- Budget-timeline match
- Pitfalls + alternatives